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Chlamydial Protease-Like Activity Factor and Type III Secreted Effectors Cooperate in Inhibition of p65 Nuclear Translocation

The chlamydial protease-like activity factor (CPAF) is hypothesized to be an important secreted virulence factor; however, challenges in denaturing its proteolytic activity have hampered attempts to identify its legitimate targets. Here, we use a genetic and proteomic approach to identify authentic...

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Detalles Bibliográficos
Autores principales: Patton, Michael John, McCorrister, Stuart, Grant, Chris, Westmacott, Garrett, Fariss, Robert, Hu, Pingzhao, Zhao, Kaiqiong, Blake, Mary, Whitmire, Bill, Yang, Chunfu, Caldwell, Harlan D., McClarty, Grant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040114/
https://www.ncbi.nlm.nih.gov/pubmed/27677792
http://dx.doi.org/10.1128/mBio.01427-16