Network-based inference of protein activity helps functionalize the genetic landscape of cancer

Identifying the multiple dysregulated oncoproteins that contribute to tumorigenesis in a given patient is crucial for developing personalized treatment plans. However, accurate inference of aberrant protein activity in biological samples is still challenging as genetic alterations are only partially...

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Detalles Bibliográficos
Autores principales: Alvarez, Mariano J., Shen, Yao, Giorgi, Federico M., Lachmann, Alexander, Ding, B. Belinda, Ye, B. Hilda, Califano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040167/
https://www.ncbi.nlm.nih.gov/pubmed/27322546
http://dx.doi.org/10.1038/ng.3593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040167/
https://www.ncbi.nlm.nih.gov/pubmed/27322546
http://dx.doi.org/10.1038/ng.3593

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