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Application of interferon modulators to overcome partial resistance of human ovarian cancers to VSV-GP oncolytic viral therapy

Previously, we described an oncolytic vesicular stomatitis virus variant pseudotyped with the nonneurotropic glycoprotein of the lymphocytic choriomeningitis virus, VSV-GP, which was highly effective in glioblastoma. Here, we tested its potency for the treatment of ovarian cancer, a leading cause of...

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Detalles Bibliográficos
Autores principales: Dold, Catherine, Rodriguez Urbiola, Carles, Wollmann, Guido, Egerer, Lisa, Muik, Alexander, Bellmann, Lydia, Fiegl, Heidelinde, Marth, Christian, Kimpel, Janine, von Laer, Dorothee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040171/
https://www.ncbi.nlm.nih.gov/pubmed/27738655
http://dx.doi.org/10.1038/mto.2016.21