Cargando…

Coordinated expression of tyro3, axl, and mer receptors in macrophage ontogeny

The TAM receptors (Tyro3, Axl, and Mer) are a family of homologous receptor-tyrosine kinases that inhibit Toll-like receptor signaling to regulate downstream pathways and restore homeostasis. TAM triple mutant mice (Tyro3(−/−), Axl(−/−), Mer(−/−)) have elevated levels of pro-inflammatory cytokines a...

Descripción completa

Detalles Bibliográficos
Autores principales: Malawista, Anna, Wang, Xiaomei, Trentalange, Mark, Allore, Heather G., Montgomery, Ruth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040214/
https://www.ncbi.nlm.nih.gov/pubmed/27695708
http://dx.doi.org/10.14800/macrophage.1261