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Coordinated expression of tyro3, axl, and mer receptors in macrophage ontogeny
The TAM receptors (Tyro3, Axl, and Mer) are a family of homologous receptor-tyrosine kinases that inhibit Toll-like receptor signaling to regulate downstream pathways and restore homeostasis. TAM triple mutant mice (Tyro3(−/−), Axl(−/−), Mer(−/−)) have elevated levels of pro-inflammatory cytokines a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040214/ https://www.ncbi.nlm.nih.gov/pubmed/27695708 http://dx.doi.org/10.14800/macrophage.1261 |