RhoA and Rac1 GTPases Differentially Regulate Agonist-Receptor Mediated Reactive Oxygen Species Generation in Platelets

Agonist induced generation of reactive oxygen species (ROS) by NADPH oxidases (NOX) enhances platelet aggregation and hence the risk of thrombosis. RhoA and Rac1 GTPases are involved in ROS generation by NOX in a variety of cells, but their roles in platelet ROS production remain unclear. In this st...

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Detalles Bibliográficos
Autores principales: Akbar, Huzoor, Duan, Xin, Saleem, Saima, Davis, Ashley K., Zheng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040254/
https://www.ncbi.nlm.nih.gov/pubmed/27681226
http://dx.doi.org/10.1371/journal.pone.0163227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040254/
https://www.ncbi.nlm.nih.gov/pubmed/27681226
http://dx.doi.org/10.1371/journal.pone.0163227

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