Alternative Splice Variants Modulates Dominant-Negative Function of Helios in T-Cell Leukemia

The molecular defects which lead to multistep incidences of human T-cell leukemia have yet to be identified. The DNA-binding protein Helios (known as IKZF2), a member of the Ikaros family of Krüppel-like zinc-finger proteins, functions pivotally in T-cell differentiation and activation. In this stud...

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Detalles Bibliográficos
Autores principales: Zhao, Shaorong, Liu, Wei, Li, Yinghui, Liu, Pengjiang, Li, Shufang, Dou, Daolei, Wang, Yue, Yang, Rongcun, Xiang, Rong, Liu, Feifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040427/
https://www.ncbi.nlm.nih.gov/pubmed/27681508
http://dx.doi.org/10.1371/journal.pone.0163328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040427/
https://www.ncbi.nlm.nih.gov/pubmed/27681508
http://dx.doi.org/10.1371/journal.pone.0163328

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