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SCOTTI: Efficient Reconstruction of Transmission within Outbreaks with the Structured Coalescent

Exploiting pathogen genomes to reconstruct transmission represents a powerful tool in the fight against infectious disease. However, their interpretation rests on a number of simplifying assumptions that regularly ignore important complexities of real data, in particular within-host evolution and no...

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Detalles Bibliográficos
Autores principales: De Maio, Nicola, Wu, Chieh-Hsi, Wilson, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040440/
https://www.ncbi.nlm.nih.gov/pubmed/27681228
http://dx.doi.org/10.1371/journal.pcbi.1005130