Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta

Imprinted genes are expressed primarily from one parental allele by virtue of a germ line epigenetic process. Achaete-scute complex homolog 2 (Ascl2 aka Mash2) is a maternally expressed imprinted gene that plays a key role in placental and intestinal development. Loss-of-function of Ascl2 results in...

Descripción completa

Detalles Bibliográficos
Autores principales: Tunster, S.J., McNamara, G.I., Creeth, H.D.J., John, R.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040514/
https://www.ncbi.nlm.nih.gov/pubmed/27542691
http://dx.doi.org/10.1016/j.ydbio.2016.08.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040514/
https://www.ncbi.nlm.nih.gov/pubmed/27542691
http://dx.doi.org/10.1016/j.ydbio.2016.08.014

Ejemplares similares