HA Antibody-Mediated FcγRIIIa Activity Is Both Dependent on FcR Engagement and Interactions between HA and Sialic Acids

Interactions with receptors for the Fc region of IgG (FcγRs) have been shown to contribute to the in vivo protection against influenza A viruses provided by broadly neutralizing antibodies (bnAbs) that bind to the viral hemagglutinin (HA) stem. In particular, Fc-mediated antibody-dependent cellular...

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Detalles Bibliográficos
Autores principales: Cox, Freek, Kwaks, Ted, Brandenburg, Boerries, Koldijk, Martin H., Klaren, Vincent, Smal, Bastiaan, Korse, Hans J. W. M., Geelen, Eric, Tettero, Lisanne, Zuijdgeest, David, Stoop, Esther J. M., Saeland, Eirikur, Vogels, Ronald, Friesen, Robert H. E., Koudstaal, Wouter, Goudsmit, Jaap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040702/
https://www.ncbi.nlm.nih.gov/pubmed/27746785
http://dx.doi.org/10.3389/fimmu.2016.00399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040702/
https://www.ncbi.nlm.nih.gov/pubmed/27746785
http://dx.doi.org/10.3389/fimmu.2016.00399

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