Calcineurin/NFAT Activation-Dependence of Leptin Synthesis and Vascular Growth in Response to Mechanical Stretch

Background and Aims: Hypertension and obesity are important risk factors of cardiovascular disease. They are both associated with high leptin levels and have been shown to promote vascular hypertrophy, through the RhoA/ROCK and ERK1/2 phosphorylation. Calcineurin/NFAT activation also induces vascula...

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Detalles Bibliográficos
Autores principales: Soudani, Nadia, Ghantous, Crystal M., Farhat, Zein, Shebaby, Wassim N., Zibara, Kazem, Zeidan, Asad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040753/
https://www.ncbi.nlm.nih.gov/pubmed/27746739
http://dx.doi.org/10.3389/fphys.2016.00433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040753/
https://www.ncbi.nlm.nih.gov/pubmed/27746739
http://dx.doi.org/10.3389/fphys.2016.00433

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