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Cloning, Sequencing, and the Expression of the Elusive Sarcomeric TPM4α Isoform in Humans

In mammals, tropomyosin is encoded by four known TPM genes (TPM1, TPM2, TPM3, and TPM4) each of which can generate a number of TPM isoforms via alternative splicing and/or using alternate promoters. In humans, the sarcomeric isoform(s) of each of the TPM genes, except for the TPM4, have been known f...

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Detalles Bibliográficos
Autores principales: Dube, Dipak K., Dube, Syamalima, Abbott, Lynn, Alshiekh-Nasany, Ruham, Mitschow, Charles, Poiesz, Bernard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040813/
https://www.ncbi.nlm.nih.gov/pubmed/27703814
http://dx.doi.org/10.1155/2016/3105478