A single molecule assay to probe monovalent and multivalent bonds between hyaluronan and its key leukocyte receptor CD44 under force

Glycosaminoglycans (GAGs), a category of linear, anionic polysaccharides, are ubiquitous in the extracellular space, and important extrinsic regulators of cell function. Despite the recognized significance of mechanical stimuli in cellular communication, however, only few single molecule methods are...

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Detalles Bibliográficos
Autores principales: Bano, Fouzia, Banerji, Suneale, Howarth, Mark, Jackson, David G., Richter, Ralf P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040960/
https://www.ncbi.nlm.nih.gov/pubmed/27679982
http://dx.doi.org/10.1038/srep34176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040960/
https://www.ncbi.nlm.nih.gov/pubmed/27679982
http://dx.doi.org/10.1038/srep34176

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