Functional Annotations of Paralogs: A Blessing and a Curse

Gene duplication followed by mutation is a classic mechanism of neofunctionalization, producing gene families with functional diversity. In some cases, a single point mutation is sufficient to change the substrate specificity and/or the chemistry performed by an enzyme, making it difficult to accura...

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Detalles Bibliográficos
Autores principales: Zallot, Rémi, Harrison, Katherine J., Kolaczkowski, Bryan, de Crécy-Lagard, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041015/
https://www.ncbi.nlm.nih.gov/pubmed/27618105
http://dx.doi.org/10.3390/life6030039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041015/
https://www.ncbi.nlm.nih.gov/pubmed/27618105
http://dx.doi.org/10.3390/life6030039

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