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Cigarette smoke reversibly activates hypoxia-inducible factor 1 in a reactive oxygen species-dependent manner

Cigarette smoke (CS) is a major contributor to the development of a large number of fatal and debilitating disorders. However, the precise molecular mechanisms underlying the effects of CS in lung disease are largely unknown. To elucidate these pathophysiological processes, we examined the in vitro...

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Detalles Bibliográficos
Autores principales: Daijo, Hiroki, Hoshino, Yuma, Kai, Shinichi, Suzuki, Kengo, Nishi, Kenichiro, Matsuo, Yoshiyuki, Harada, Hiroshi, Hirota, Kiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041075/
https://www.ncbi.nlm.nih.gov/pubmed/27680676
http://dx.doi.org/10.1038/srep34424