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Blocking Notch signal in myeloid cells alleviates hepatic ischemia reperfusion injury by repressing the activation of NF-κB through CYLD

Ischemia-reperfusion (I/R) is a major reason of hepatocyte injury during liver surgery and transplantation. Myeloid cells including macrophages and neutrophils play important roles in sustained tissue inflammation and damage, but the mechanisms regulating myeloid cells activity have been elusive. In...

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Detalles Bibliográficos
Autores principales: Yu, Heng-Chao, Bai, Lu, Yang, Zhao-Xu, Qin, Hong-Yan, Tao, Kai-Shan, Han, Hua, Dou, Ke-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041084/
https://www.ncbi.nlm.nih.gov/pubmed/27680285
http://dx.doi.org/10.1038/srep32226