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Blocking Notch signal in myeloid cells alleviates hepatic ischemia reperfusion injury by repressing the activation of NF-κB through CYLD
Ischemia-reperfusion (I/R) is a major reason of hepatocyte injury during liver surgery and transplantation. Myeloid cells including macrophages and neutrophils play important roles in sustained tissue inflammation and damage, but the mechanisms regulating myeloid cells activity have been elusive. In...
Autores principales: | Yu, Heng-Chao, Bai, Lu, Yang, Zhao-Xu, Qin, Hong-Yan, Tao, Kai-Shan, Han, Hua, Dou, Ke-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041084/ https://www.ncbi.nlm.nih.gov/pubmed/27680285 http://dx.doi.org/10.1038/srep32226 |
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