Structure-based discovery of two antiviral inhibitors targeting the NS3 helicase of Japanese encephalitis virus

Japanese encephalitis virus (JEV) is a flavivirus that threatens more than half of the world’s population. Vaccination can prevent the disease, but no specific antiviral drug is yet available for clinical therapy, and the death rate caused by JEV can reach as high as 60%. The C-terminus of non-struc...

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Detalles Bibliográficos
Autores principales: Fang, Jin’e, Li, Huan, Kong, Dexin, Cao, Shengbo, Peng, Guiqing, Zhou, Rui, Chen, Huanchun, Song, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041104/
https://www.ncbi.nlm.nih.gov/pubmed/27679979
http://dx.doi.org/10.1038/srep34550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041104/
https://www.ncbi.nlm.nih.gov/pubmed/27679979
http://dx.doi.org/10.1038/srep34550

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