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Structure-based discovery of two antiviral inhibitors targeting the NS3 helicase of Japanese encephalitis virus
Japanese encephalitis virus (JEV) is a flavivirus that threatens more than half of the world’s population. Vaccination can prevent the disease, but no specific antiviral drug is yet available for clinical therapy, and the death rate caused by JEV can reach as high as 60%. The C-terminus of non-struc...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041104/ https://www.ncbi.nlm.nih.gov/pubmed/27679979 http://dx.doi.org/10.1038/srep34550 |