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Mechanisms for the inhibition of amyloid aggregation by small ligands

The formation of amyloid aggregates is the hallmark of systemic and neurodegenerative disorders, also known as amyloidoses. Many proteins have been found to aggregate into amyloid-like fibrils and this process is recognized as a general tendency of polypeptides. Lysozyme, an antibacterial protein, i...

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Detalles Bibliográficos
Autores principales: Ramazzotti, Matteo, Melani, Fabrizio, Marchi, Laura, Mulinacci, Nadia, Gestri, Stefano, Tiribilli, Bruno, Degl'Innocenti, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041158/
https://www.ncbi.nlm.nih.gov/pubmed/27512096
http://dx.doi.org/10.1042/BSR20160101