Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserve

Granulosa cells (GCs) are tightly associated with fertility and the fate of ovarian follicles. Mitochondria are the central executers of apoptosis. However, the genetic basis underlying mitochondrial modulation in GCs during the ovarian development is poorly understood. Here, CRISPR/Cas9-mediated ge...

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Detalles Bibliográficos
Autores principales: Dong, Z, Huang, M, Liu, Z, Xie, P, Dong, Y, Wu, X, Qu, Z, Shen, B, Huang, X, Zhang, T, Li, J, Liu, J, Yanase, T, Zhou, C, Xu, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041189/
https://www.ncbi.nlm.nih.gov/pubmed/27206316
http://dx.doi.org/10.1038/cdd.2016.47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041189/
https://www.ncbi.nlm.nih.gov/pubmed/27206316
http://dx.doi.org/10.1038/cdd.2016.47

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