Splicing controls the ubiquitin response during DNA double-strand break repair

Although evidence that splicing regulates DNA repair is accumulating, the underlying mechanism(s) remain unclear. Here, we report that short-term inhibition of pre-mRNA splicing by spliceosomal inhibitors impairs cellular repair of DNA double-strand breaks. Indeed, interference with splicing as litt...

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Detalles Bibliográficos
Autores principales: Pederiva, C, Böhm, S, Julner, A, Farnebo, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041194/
https://www.ncbi.nlm.nih.gov/pubmed/27315300
http://dx.doi.org/10.1038/cdd.2016.58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041194/
https://www.ncbi.nlm.nih.gov/pubmed/27315300
http://dx.doi.org/10.1038/cdd.2016.58

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