The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca(2+) flux from the endoplasmic reticulum to mitochondria

Metalloprotease-processed CD95L (cl-CD95L) is a soluble cytokine that implements a PI3K/Ca(2+) signaling pathway in triple-negative breast cancer (TNBC) cells. Accordingly, high levels of cl-CD95L in TNBC women correlate with poor prognosis, and administration of this ligand in an orthotopic xenogra...

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Detalles Bibliográficos
Autores principales: Fouqué, A, Lepvrier, E, Debure, L, Gouriou, Y, Malleter, M, Delcroix, V, Ovize, M, Ducret, T, Li, C, Hammadi, M, Vacher, P, Legembre, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041197/
https://www.ncbi.nlm.nih.gov/pubmed/27367565
http://dx.doi.org/10.1038/cdd.2016.61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041197/
https://www.ncbi.nlm.nih.gov/pubmed/27367565
http://dx.doi.org/10.1038/cdd.2016.61

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