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CCL18 synergises with high concentrations of glucose in stimulating fibronectin production in human renal tubuloepithelial cells

BACKGROUND: Diabetic nephropathy is the leading cause of end stage kidney disease worldwide. The pathogenesis of this disease remains elusive and multiple factors have been implicated. These include the effects of hyperglycaemia, haemodynamic and metabolic factors, and an inflammatory process that s...

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Detalles Bibliográficos
Autores principales: Montero, Rosa M., Bhangal, Gurjeet, Pusey, Charles D., Frankel, Andrew H., Tam, Frederick W. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041317/
https://www.ncbi.nlm.nih.gov/pubmed/27686838
http://dx.doi.org/10.1186/s12882-016-0352-1