Preparation and preclinical evaluation of (68)Ga-DOTA-amlodipine for L-type calcium channel imaging

AIM: In order to develop a possible tracer for L-type calcium channel imaging, we here report the development of a Ga-68 amlodipine derivative for possible PET imaging. MATERIALS AND METHODS: Amlodipine DOTA conjugate was synthesized, characterized and went through calcium channel blockade, toxicity...

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Detalles Bibliográficos
Autores principales: Firuzyar, Tahereh, Jalilian, Amir Reza, Aboudzadeh, Mohammad Reza, Sadeghpour, Hossein, Shafiee-Ardestani, Mahdi, Khalaj, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041414/
https://www.ncbi.nlm.nih.gov/pubmed/27833311
http://dx.doi.org/10.4103/0972-3919.190797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041414/
https://www.ncbi.nlm.nih.gov/pubmed/27833311
http://dx.doi.org/10.4103/0972-3919.190797

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