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Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells

BACKGROUND: Adoptive immunotherapy is gaining momentum to fight malignancies, whereby γδ T cells have received recent attention as an alternative cell source as to natural killer cells and αβ T cells. The advent of γδ T cells is largely due to their ability to recognize and target tumor cells using...

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Detalles Bibliográficos
Autores principales: Van Acker, Heleen H., Anguille, Sébastien, Willemen, Yannick, Van den Bergh, Johan M., Berneman, Zwi N., Lion, Eva, Smits, Evelien L., Van Tendeloo, Viggo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041439/
https://www.ncbi.nlm.nih.gov/pubmed/27686372
http://dx.doi.org/10.1186/s13045-016-0329-3