Cargando…

Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells

BACKGROUND: Adoptive immunotherapy is gaining momentum to fight malignancies, whereby γδ T cells have received recent attention as an alternative cell source as to natural killer cells and αβ T cells. The advent of γδ T cells is largely due to their ability to recognize and target tumor cells using...

Descripción completa

Detalles Bibliográficos
Autores principales:	Van Acker, Heleen H., Anguille, Sébastien, Willemen, Yannick, Van den Bergh, Johan M., Berneman, Zwi N., Lion, Eva, Smits, Evelien L., Van Tendeloo, Viggo F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041439/ https://www.ncbi.nlm.nih.gov/pubmed/27686372 http://dx.doi.org/10.1186/s13045-016-0329-3

Ejemplares similares

Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner
por: Anguille, Sébastien, et al.
Publicado: (2015)

Transpresentation of interleukin-15 by IL-15/IL-15Rα mRNA-engineered human dendritic cells boosts antitumoral natural killer cell activity
por: Van den Bergh, Johan, et al.
Publicado: (2015)

Interleukin-15-Cultured Dendritic Cells Enhance Anti-Tumor Gamma Delta T Cell Functions through IL-15 Secretion
por: Van Acker, Heleen H., et al.
Publicado: (2018)

Empowering gamma delta T cells with antitumor immunity by dendritic cell-based immunotherapy
por: Van Acker, Heleen H, et al.
Publicado: (2015)

Desirable cytolytic immune effector cell recruitment by interleukin-15 dendritic cells
por: Van Acker, Heleen H., et al.
Publicado: (2017)

CD56 Homodimerization and Participation in Anti-Tumor Immune Effector Cell Functioning: A Role for Interleukin-15
por: Van Acker, Heleen H., et al.
Publicado: (2019)

Poly(I:C) Enhances the Susceptibility of Leukemic Cells to NK Cell Cytotoxicity and Phagocytosis by DC
por: Lion, Eva, et al.
Publicado: (2011)

In vitro expansion of Wilms’ tumor protein 1 epitope-specific primary T cells from healthy human peripheral blood mononuclear cells
por: van der Heijden, Sanne, et al.
Publicado: (2023)

Dendritic Cell-Based Immunotherapy of Acute Myeloid Leukemia
por: Van Acker, Heleen H., et al.
Publicado: (2019)

Interleukin-15-Induced CD56(+) Myeloid Dendritic Cells Combine Potent Tumor Antigen Presentation with Direct Tumoricidal Potential
por: Anguille, Sébastien, et al.
Publicado: (2012)

Correction: Interleukin-15-Induced CD56(+) Myeloid Dendritic Cells Combine Potent Tumor Antigen Presentation with Direct Tumoricidal Potential
por: Anguille, Sébastien, et al.
Publicado: (2014)

Dendritic Cell-Based and Other Vaccination Strategies for Pediatric Cancer
por: de Bruijn, Sévérine, et al.
Publicado: (2019)

Short-term cultured, interleukin-15 differentiated dendritic cells have potent immunostimulatory properties
por: Anguille, Sébastien, et al.
Publicado: (2009)

Anti-Tumor Potency of Short-Term Interleukin-15 Dendritic Cells Is Potentiated by In Situ Silencing of Programmed-Death Ligands
por: Versteven, Maarten, et al.
Publicado: (2022)

The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells
por: Willemen, Yannick, et al.
Publicado: (2016)

HPV vaccine stimulates cytotoxic activity of killer dendritic cells and natural killer cells against HPV-positive tumour cells
por: Van den Bergh, Johan M J, et al.
Publicado: (2014)

Chimeric Antigen Receptor-Modified T Cell Therapy in Multiple Myeloma: Beyond B Cell Maturation Antigen
por: Timmers, Marijke, et al.
Publicado: (2019)

CD56 in the Immune System: More Than a Marker for Cytotoxicity?
por: Van Acker, Heleen H., et al.
Publicado: (2017)

Efficient and Non-genotoxic RNA-Based Engineering of Human T Cells Using Tumor-Specific T Cell Receptors With Minimal TCR Mispairing
por: Campillo-Davo, Diana, et al.
Publicado: (2018)

The Ins and Outs of Messenger RNA Electroporation for Physical Gene Delivery in Immune Cell-Based Therapy
por: Campillo-Davo, Diana, et al.
Publicado: (2021)

Rapid Assessment of Functional Avidity of Tumor-Specific T Cell Receptors Using an Antigen-Presenting Tumor Cell Line Electroporated with Full-Length Tumor Antigen mRNA
por: Campillo-Davo, Diana, et al.
Publicado: (2020)

Ribonucleic Acid Engineering of Dendritic Cells for Therapeutic Vaccination: Ready ‘N Able to Improve Clinical Outcome?
por: Willemen, Yannick, et al.
Publicado: (2020)

Interferon α may be back on track to treat acute myeloid leukemia
por: Smits, Evelien L.J.M., et al.
Publicado: (2013)

Regulatory T Cells and Human Disease
por: Cools, Nathalie, et al.
Publicado: (2007)

Induction of HIV-specific T-cell responses by gag
por: Van Gulck, Ellen, et al.
Publicado: (2006)

Induction of Cytomegalovirus-Specific T Cell Responses in Healthy Volunteers and Allogeneic Stem Cell Recipients Using Vaccination With Messenger RNA–Transfected Dendritic Cells
por: Van Craenenbroeck, Amaryllis H., et al.
Publicado: (2015)

Dendritic Cells and Programmed Death-1 Blockade: A Joint Venture to Combat Cancer
por: Versteven, Maarten, et al.
Publicado: (2018)

Sensitive detection of human papillomavirus type 16 E7-specific T cells by ELISPOT after multiple in vitro stimulations of CD8(+ )T cells with peptide-pulsed autologous dendritic cells
por: Cools, Nathalie, et al.
Publicado: (2006)

Interleukin-12p70 Expression by Dendritic Cells of HIV-1-Infected Patients Fails to Stimulate gag-Specific Immune Responses
por: Van Gulck, Ellen, et al.
Publicado: (2012)

BDCA1+CD14+ Immunosuppressive Cells in Cancer, a Potential Target?
por: van Ee, Thomas J., et al.
Publicado: (2018)

Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use
por: Van den Bergh, J. M. J., et al.
Publicado: (2017)

A versatile T cell-based assay to assess therapeutic antigen-specific PD-1-targeted approaches
por: Versteven, Maarten, et al.
Publicado: (2018)

Stimulatory and inhibitory activity of STING ligands on tumor-reactive human gamma/delta T cells
por: Serrano, Ruben, et al.
Publicado: (2022)

Sampling Site Matters When Counting Lymphocyte Subpopulations
por: Ogunjimi, Benson, et al.
Publicado: (2012)

Stimulation of antiviral cellular immune responses by therapeutic vaccination of HIV-1-infected patients with dendritic cells transfected with gag, tat, rev and nef mRNA
por: Van Gulck, Ellen, et al.
Publicado: (2011)

CD56 marks human dendritic cell subsets with cytotoxic potential
por: Roothans, Dessie, et al.
Publicado: (2013)

Non-V delta 2 gamma delta T lymphocytes as effectors of cancer immunotherapy
por: Fisher, Jonathan, et al.
Publicado: (2014)

Plasmid-based genetic modification of human bone marrow-derived stromal cells: analysis of cell survival and transgene expression after transplantation in rat spinal cord
por: Ronsyn, Mark W, et al.
Publicado: (2007)

Two for one: targeting BCMA and CD19 in B-cell malignancies with off-the-shelf dual-CAR NK-92 cells
por: Roex, Gils, et al.
Publicado: (2022)

New targets for therapy: antigen identification in adults with B-cell acute lymphoblastic leukaemia
por: Jordaens, Stephanie, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9b4605ppstr6rl9vnv33sdtaht