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Human mutations affect the epigenetic/bookmarking function of HNF1B

Bookmarking factors are transcriptional regulators involved in the mitotic transmission of epigenetic information via their ability to remain associated with mitotic chromatin. The mechanisms through which bookmarking factors bind to mitotic chromatin remain poorly understood. HNF1β is a bookmarking...

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Detalles Bibliográficos
Autores principales: Lerner, Jonathan, Bagattin, Alessia, Verdeguer, Francisco, Makinistoglu, Munevver P., Garbay, Serge, Felix, Tristan, Heidet, Laurence, Pontoglio, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041451/
https://www.ncbi.nlm.nih.gov/pubmed/27229139
http://dx.doi.org/10.1093/nar/gkw467