FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function

Forkhead box A1 (FOXA1) is an FKHD family protein that plays pioneering roles in lineage-specific enhancer activation and gene transcription. Through genome-wide location analyses, here we show that FOXA1 expression and occupancy are, in turn, required for the maintenance of these epigenetic signatu...

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Detalles Bibliográficos
Autores principales: Yang, Yeqing A., Zhao, Jonathan C., Fong, Ka-wing, Kim, Jung, Li, Shangze, Song, Chunxiao, Song, Bing, Zheng, Bin, He, Chuan, Yu, Jindan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041455/
https://www.ncbi.nlm.nih.gov/pubmed/27257062
http://dx.doi.org/10.1093/nar/gkw498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041455/
https://www.ncbi.nlm.nih.gov/pubmed/27257062
http://dx.doi.org/10.1093/nar/gkw498

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