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Synergy and antagonism in regulation of recombinant human INO80 chromatin remodeling complex

We have purified a minimal core human Ino80 complex from recombinant protein expressed in insect cells. The complex comprises one subunit each of an N-terminally truncated Ino80, actin, Arp4, Arp5, Arp8, Ies2 and Ies6, together with a single heterohexamer of the Tip49a and Tip49b proteins. This core...

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Detalles Bibliográficos
Autores principales: Willhoft, Oliver, Bythell-Douglas, Rohan, McCormack, Elizabeth A., Wigley, Dale B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041457/
https://www.ncbi.nlm.nih.gov/pubmed/27257055
http://dx.doi.org/10.1093/nar/gkw509