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Unexpected DNA context-dependence identifies a new determinant of Chi recombination hotspots

Homologous recombination occurs especially frequently near special chromosomal sites called hotspots. In Escherichia coli, Chi hotspots control RecBCD enzyme, a protein machine essential for the major pathway of DNA break-repair and recombination. RecBCD generates recombinogenic single-stranded DNA...

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Detalles Bibliográficos
Autores principales: Taylor, Andrew F., Amundsen, Susan K., Smith, Gerald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041463/
https://www.ncbi.nlm.nih.gov/pubmed/27330137
http://dx.doi.org/10.1093/nar/gkw541