Ctp1-dependent clipping and resection of DNA double-strand breaks by Mre11 endonuclease complex are not genetically separable

Homologous recombination (HR) repair of programmed meiotic double-strand breaks (DSBs) requires endonucleolytic clipping of Rec12(Spo11)-oligonucleotides from 5′ DNA ends followed by resection to generate invasive 3′ single-stranded DNA tails. The Mre11-Rad50-Nbs1 (MRN) endonuclease and Ctp1 (CtIP a...

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Detalles Bibliográficos
Autores principales: Jensen, Kristi L., Russell, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041466/
https://www.ncbi.nlm.nih.gov/pubmed/27325741
http://dx.doi.org/10.1093/nar/gkw557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041466/
https://www.ncbi.nlm.nih.gov/pubmed/27325741
http://dx.doi.org/10.1093/nar/gkw557

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