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Chromosome territory relocation during DNA repair requires nuclear myosin 1 recruitment to chromatin mediated by ϒ-H2AX signaling

During DNA damage response (DDR), certain gene rich chromosome territories (CTs) relocate to newer positions within interphase nuclei and revert to their native locations following repair. Such dynamic relocation of CTs has been observed under various cellular conditions, however, the underlying mec...

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Detalles Bibliográficos
Autores principales: Kulashreshtha, Mugdha, Mehta, Ishita S., Kumar, Pradeep, Rao, Basuthkar J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041470/
https://www.ncbi.nlm.nih.gov/pubmed/27365048
http://dx.doi.org/10.1093/nar/gkw573