Combination probes with intercalating anchors and proximal fluorophores for DNA and RNA detection

A new class of modified oligonucleotides (combination probes) has been designed and synthesised for use in genetic analysis and RNA detection. Their chemical structure combines an intercalating anchor with a reporter fluorophore on the same thymine nucleobase. The intercalator (thiazole orange or be...

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Detalles Bibliográficos
Autores principales: Qiu, Jieqiong, Wilson, Adam, El-Sagheer, Afaf H., Brown, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041472/
https://www.ncbi.nlm.nih.gov/pubmed/27369379
http://dx.doi.org/10.1093/nar/gkw579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041472/
https://www.ncbi.nlm.nih.gov/pubmed/27369379
http://dx.doi.org/10.1093/nar/gkw579

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