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Combination probes with intercalating anchors and proximal fluorophores for DNA and RNA detection

A new class of modified oligonucleotides (combination probes) has been designed and synthesised for use in genetic analysis and RNA detection. Their chemical structure combines an intercalating anchor with a reporter fluorophore on the same thymine nucleobase. The intercalator (thiazole orange or be...

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Detalles Bibliográficos
Autores principales:	Qiu, Jieqiong, Wilson, Adam, El-Sagheer, Afaf H., Brown, Tom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041472/ https://www.ncbi.nlm.nih.gov/pubmed/27369379 http://dx.doi.org/10.1093/nar/gkw579

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