DNA binding proteins explore multiple local configurations during docking via rapid rebinding

Finding the target site and associating in a specific orientation are essential tasks for DNA-binding proteins. In order to make the target search process as efficient as possible, proteins should not only rapidly diffuse to the target site but also dynamically explore multiple local configurations...

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Detalles Bibliográficos
Autores principales: Ganji, Mahipal, Docter, Margreet, Le Grice, Stuart F.J., Abbondanzieri, Elio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041478/
https://www.ncbi.nlm.nih.gov/pubmed/27471033
http://dx.doi.org/10.1093/nar/gkw666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041478/
https://www.ncbi.nlm.nih.gov/pubmed/27471033
http://dx.doi.org/10.1093/nar/gkw666

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