The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation

RNA-binding proteins (RBPs) play crucial roles in all organisms. The protein Gemin5 harbors two functional domains. The N-terminal domain binds to snRNAs targeting them for snRNPs assembly, while the C-terminal domain binds to IRES elements through a non-canonical RNA-binding site. Here we report a...

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Detalles Bibliográficos
Autores principales: Francisco-Velilla, Rosario, Fernandez-Chamorro, Javier, Ramajo, Jorge, Martinez-Salas, Encarnación
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041490/
https://www.ncbi.nlm.nih.gov/pubmed/27507887
http://dx.doi.org/10.1093/nar/gkw702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041490/
https://www.ncbi.nlm.nih.gov/pubmed/27507887
http://dx.doi.org/10.1093/nar/gkw702

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