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Conformation-dependent restraints for polynucleotides: I. Clustering of the geometry of the phosphodiester group

The refinement of macromolecular structures is usually aided by prior stereochemical knowledge in the form of geometrical restraints. Such restraints are also used for the flexible sugar-phosphate backbones of nucleic acids. However, recent highly accurate structural studies of DNA suggest that the...

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Detalles Bibliográficos
Autores principales: Kowiel, Marcin, Brzezinski, Dariusz, Jaskolski, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041494/
https://www.ncbi.nlm.nih.gov/pubmed/27521371
http://dx.doi.org/10.1093/nar/gkw717