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Conformation-dependent restraints for polynucleotides: I. Clustering of the geometry of the phosphodiester group
The refinement of macromolecular structures is usually aided by prior stereochemical knowledge in the form of geometrical restraints. Such restraints are also used for the flexible sugar-phosphate backbones of nucleic acids. However, recent highly accurate structural studies of DNA suggest that the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041494/ https://www.ncbi.nlm.nih.gov/pubmed/27521371 http://dx.doi.org/10.1093/nar/gkw717 |