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Conservation of context-dependent splicing activity in distant Muscleblind homologs

The Muscleblind (MBL) protein family is a deeply conserved family of RNA binding proteins that regulate alternative splicing, alternative polyadenylation, RNA stability and RNA localization. Their inactivation due to sequestration by expanded CUG repeats causes symptoms in the neuromuscular disease...

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Detalles Bibliográficos
Autores principales: Oddo, Julia C., Saxena, Tanvi, McConnell, Ona L., Berglund, J. Andrew, Wang, Eric T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041496/
https://www.ncbi.nlm.nih.gov/pubmed/27557707
http://dx.doi.org/10.1093/nar/gkw735