Mycobacterium tuberculosis Rv3628 drives Th1-type T cell immunity via TLR2-mediated activation of dendritic cells and displays vaccine potential against the hyper-virulent Beijing K strain

Identification of vaccine target antigens (Ags) that induce Ag-specific Th1 immunity is the first step toward the development of a tuberculosis vaccine. Here, we evaluated the Mycobacterium tuberculosis (Mtb) protein Rv3628, a soluble inorganic pyrophosphatase, as a vaccine target and characterized...

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Detalles Bibliográficos
Autores principales: Kim, Woo Sik, Kim, Jong-Seok, Cha, Seung Bin, Kim, Hongmin, Kwon, Kee Woong, Kim, So Jeong, Han, Seung Jung, Choi, Soo Young, Cho, Sang-Nae, Park, Jong-Hwan, Shin, Sung Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041883/
https://www.ncbi.nlm.nih.gov/pubmed/27097115
http://dx.doi.org/10.18632/oncotarget.8771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041883/
https://www.ncbi.nlm.nih.gov/pubmed/27097115
http://dx.doi.org/10.18632/oncotarget.8771

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