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ImmunoPET helps predicting the efficacy of antibody-drug conjugates targeting TENB2 and STEAP1
The efficacy of antibody-drug conjugates (ADCs) targeted to solid tumors depends on biological processes that are hard to monitor in vivo. (89)Zr-immunoPET of the ADC antibodies could help understand the performance of ADCs in the clinic by confirming the necessary penetration, binding, and internal...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041891/ https://www.ncbi.nlm.nih.gov/pubmed/27029064 http://dx.doi.org/10.18632/oncotarget.8390 |