ImmunoPET helps predicting the efficacy of antibody-drug conjugates targeting TENB2 and STEAP1

The efficacy of antibody-drug conjugates (ADCs) targeted to solid tumors depends on biological processes that are hard to monitor in vivo. (89)Zr-immunoPET of the ADC antibodies could help understand the performance of ADCs in the clinic by confirming the necessary penetration, binding, and internal...

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Detalles Bibliográficos
Autores principales: Williams, Simon-Peter, Ogasawara, Annie, Tinianow, Jeff N., Flores, Judith E., Kan, David, Lau, Jeffrey, Go, MaryAnn, Vanderbilt, Alexander N., Gill, Herman S., Miao, Li, Goldsmith, Joshua, Rubinfeld, Bonnee, Mao, Weiguang, Firestein, Ron, Yu, Shang-Fan, Marik, Jan, Terwisscha van Scheltinga, Anton G.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041891/
https://www.ncbi.nlm.nih.gov/pubmed/27029064
http://dx.doi.org/10.18632/oncotarget.8390

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