Differential regulation of the c-Myc/Lin28 axis discriminates subclasses of rearranged MLL leukemia

MLL rearrangements occur in myeloid and lymphoid leukemias and are generally associated with a poor prognosis, however this varies depending on the fusion partner. We modeled acute myeloid leukemia (AML) in mice using various MLL fusion proteins (MLL-FPs) and observed significantly different surviva...

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Detalles Bibliográficos
Autores principales: Chen, Lili, Sun, Yuqing, Wang, Jingya, Jiang, Hui, Muntean, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041898/
https://www.ncbi.nlm.nih.gov/pubmed/27007052
http://dx.doi.org/10.18632/oncotarget.8199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041898/
https://www.ncbi.nlm.nih.gov/pubmed/27007052
http://dx.doi.org/10.18632/oncotarget.8199

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