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Differential regulation of the c-Myc/Lin28 axis discriminates subclasses of rearranged MLL leukemia
MLL rearrangements occur in myeloid and lymphoid leukemias and are generally associated with a poor prognosis, however this varies depending on the fusion partner. We modeled acute myeloid leukemia (AML) in mice using various MLL fusion proteins (MLL-FPs) and observed significantly different surviva...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041898/ https://www.ncbi.nlm.nih.gov/pubmed/27007052 http://dx.doi.org/10.18632/oncotarget.8199 |