Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer

The JNK and P38α pathways play a crucial role in tissue homeostasis, apoptosis and autophagy under genotoxic stresses, but it is unclear whether single nucleotide polymorphisms (SNPs) of genes in these pathways play a role in platinum-based chemotherapy-induced toxicities in patients with advanced n...

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Detalles Bibliográficos
Autores principales: Jia, Ming, Zhu, Meiling, Wang, Mengyun, Sun, Menghong, Qian, Ji, Ding, Fei, Chang, Jianhua, Wei, Qingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041904/
https://www.ncbi.nlm.nih.gov/pubmed/26993769
http://dx.doi.org/10.18632/oncotarget.8052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041904/
https://www.ncbi.nlm.nih.gov/pubmed/26993769
http://dx.doi.org/10.18632/oncotarget.8052

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