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Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer
The JNK and P38α pathways play a crucial role in tissue homeostasis, apoptosis and autophagy under genotoxic stresses, but it is unclear whether single nucleotide polymorphisms (SNPs) of genes in these pathways play a role in platinum-based chemotherapy-induced toxicities in patients with advanced n...
Autores principales: | Jia, Ming, Zhu, Meiling, Wang, Mengyun, Sun, Menghong, Qian, Ji, Ding, Fei, Chang, Jianhua, Wei, Qingyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041904/ https://www.ncbi.nlm.nih.gov/pubmed/26993769 http://dx.doi.org/10.18632/oncotarget.8052 |
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