Chronic TGFβ stimulation promotes the metastatic potential of lung cancer cells by Snail protein stabilization through integrin β3-Akt-GSK3β signaling

Chronic exposure to TGFβ, a frequent occurrence for tumor cells in the tumor microenvironment, confers more aggressive phenotypes on cancer cells by promoting their invasion and migration while at the same time increasing their resistance to the growth-inhibitory effect of TGFβ. In this study, a tra...

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Detalles Bibliográficos
Autores principales: Bae, Gab-Yong, Hong, Soon-Ki, Park, Jeong-Rak, Kwon, Ok-Seon, Kim, Keun-Tae, Koo, JaeHyung, Oh, Ensel, Cha, Hyuk-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041910/
https://www.ncbi.nlm.nih.gov/pubmed/27015122
http://dx.doi.org/10.18632/oncotarget.8295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041910/
https://www.ncbi.nlm.nih.gov/pubmed/27015122
http://dx.doi.org/10.18632/oncotarget.8295

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