mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cells

Karyopherin subunit alpha-2 (KPNA2) is overexpressed in various human cancers and is associated with cancer invasiveness and poor prognosis in patient. Nevertheless, the regulation of KPNA2 expression in cancers remains unclear. We herein applied epidermal growth factor (EGF) and five EGF receptor (...

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Detalles Bibliográficos
Autores principales: Wang, Chun-I, Chen, Yan-Yu, Wang, Chih-Liang, Yu, Jau-Song, Chang, Yu-Sun, Yu, Chia-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041915/
https://www.ncbi.nlm.nih.gov/pubmed/27009856
http://dx.doi.org/10.18632/oncotarget.8170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041915/
https://www.ncbi.nlm.nih.gov/pubmed/27009856
http://dx.doi.org/10.18632/oncotarget.8170

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