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ERK2 phosphorylation of EBNA1 serine 383 residue is important for EBNA1-dependent transactivation

Functional inhibition of Epstein-Barr virus (EBV)-encoded nuclear antigen 1 (EBNA1) can cause the death of EBV infected cells. In this study, a bioinformatics tool predicted the existence of putative extracellular signal-regulated kinase (ERK) docking and substrate consensus sites on EBNA1, suggesti...

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Detalles Bibliográficos
Autores principales: Noh, Ka-Won, Park, Jihyun, Joo, Eun Hye, Lee, Eun Kyung, Choi, Eun Young, Kang, Myung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041921/
https://www.ncbi.nlm.nih.gov/pubmed/27009860
http://dx.doi.org/10.18632/oncotarget.8177