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Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M

Numb is a multifunctional protein involved in diverse cellular processes. However, the function of Numb in kidney remains unclear. Here, we reported that Numb is expressed in renal tubules and glomeruli in normal adult kidney. Numb expression was upregulated in fibrotic kidneys induced by unilateral...

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Detalles Bibliográficos
Autores principales: Zhu, Fengxin, Liu, Wei, Li, Tang, Wan, Jiao, Tian, Jianwei, Zhou, Zhanmei, Li, Hao, Liu, Youhua, Hou, Fan Fan, Nie, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041930/
https://www.ncbi.nlm.nih.gov/pubmed/27016419
http://dx.doi.org/10.18632/oncotarget.8238